| 授業方針・テーマ |
Recent and future topics on evolutionary biology based on population genetics, molecular phylogenetics will be deeply introduced. Darwin’s theory of natural selection and the neutral theory of molecular evolution will also be introduced. Biodiversity as a consequence of evolution will also be introduced with a couple of examples. |
習得できる知識・能力や授業の 目的・到達目標 |
First half (Nozawa): Students are expected to understand how to construct molecular phylogeny. Students are also expected to understand major components of genomes and explain the mechanism of genome evolution. They will be able to explain the effect of epigenetics on evolution. Finally, students aim to grasp the basics on how to analyze large-scale sequence data and apply to evolutionary studies. Second half (Tachiki): This course introduces the concept of adaptive evolution since Darwin’s On the Origin of Species and develops a rigorous understanding of "fitness" as a quantitative measure of adaptation. The primary objective is to enable students to apply appropriate fitness measures when discussing adaptive processes in biological systems. |
授業計画・内容 授業方法 |
This course will be provided in a lecture format. The content for each class is as follows.
First half (Nozawa): 1. Evolution and phylogeny 2. Genome evolution 1: gene duplication 3. Genome evolution 2: transposable elements 4. Epigenetics 1 5. Epigenetics 2 6. Data analyses in evolution 1 7. Data analyses in evolution 2 8. Summary of the first part
Second half (Tachiki) 9. What is fitness? On the Origin of Species and Darwinism 10. Kimura’s Neutral Theory and fixation probability 11. Adaptive evolution from a perspective of population genetics 12. Ecology and fitness 13. Evolutionary game theory 14. Evolutionary games in finite populations 15. Modes of selection: sexual selection and kin selection |
| 授業外学習 |
Nozawa: Students are required to review the content of each class. Tachiki: Students are encouraged to explore topics of personal interest related to the course material.
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| テキスト・参考書等 |
Nozawa: handouts will be uploaded to kibaco. Tachiki: Course materials will be distributed via kibaco. The following books are recommended as supplementary reading: On the Origin of Species (by Darwin) A Biologist's Guide to Mathematical Modeling in Ecology and Evolution (by Otto & Day, Princeton Univ Press) |
| 成績評価方法 |
Nozawa: participation (including response to questions, discussions, and small quiz) 30%, examination 70% Tachiki: Class participation (including short written assignments and engagement during lectures): 30% & Final examination: 70%
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質問受付方法 (オフィスアワー等) |
There is no particular office hour. Students can ask questions at any time to Nozawa (first half, manozawa[at]tmu.ac.jp) or Tachiki (second half, tachiki[at]tmu.ac.jp). |
特記事項 (他の授業科目との関連性) |
It is strongly advisable to take “進化生物学概論/General evolutionary biology” in advance.
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| 備考 |
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